Nicole de Boer began her acting career as a child in her native Toronto, Canada.  Nicole's numerous television credits include:  "Beyond Reality" (1991), "First Resort" (1990), "Catwalk" (1992), "The Kids in the Hall" (1988), "The Outer Limits" (1995), "PSI Factor: Chronicles of the Paranormal" (1996), "Maniac Mansion" (1990) and "Deepwater Black" (1997) (aka Mission Genesis).

On film, she was featured in Kids in the Hall: Brain Candy (1996), co-starred in the film National Lampoon's Senior Trip (1995) with Matt Frewer and Tommy Chong and was in the critically received Sci-Fi movie, Cube (1997). While filming the series "Dooley Gardens" (1999) in Newfoundland, she got the call and was cast in the 7th and final season of "Star Trek: Deep Space Nine" (1993), replacing Terry Farrell as the Dax symbiont' host.  Playing Lt. Ezri Dax.

Most recently played , Sarah Bannerman, in the TV series "Dead Zone".